Publications by authors named "A Raynaud-Simon"

Article Synopsis
  • Overuse of antibiotics in nursing homes often leads to negative outcomes and the rise of resistant bacteria, prompting the need for better antimicrobial stewardship interventions.
  • This study conducted interviews with prescribing physicians in nursing homes in France to determine factors influencing antibiotic prescribing, resources used, and necessary interventions.
  • Key findings revealed that perceived risks, difficulties in obtaining microbiological samples, and staff shortages contribute to inappropriate prescribing practices, while tailored guidelines and enhanced multidisciplinary communication could improve antibiotic use.
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Article Synopsis
  • The study investigates the relationship between plasma neurofilament light (NfL) protein levels and cognitive impairment across various patient groups, including Alzheimer’s disease and other dementias.
  • The research was conducted on 320 patients, measuring NfL levels and assessing cognitive performance, with significant associations found between higher NfL levels and lower cognition, particularly in memory and executive functions.
  • Despite noteworthy findings, the clinical application of plasma NfL in daily practice for unselected cognitive impairment patients remains largely unaddressed.
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Background: During the first COVID-19 pandemic wave (1st CoPW), nursing homes (NHs) experienced a high rate of COVID-19 infection and death. Residents who survived the COVID-19 infection may have become frailer. This study aimed to determine the predictive value of having a COVID-19 infection during the 1st CoPW for 2-year mortality in NH residents.

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Background: Respiratory syncytial virus (RSV) is widely recognized as a cause of acute respiratory failure in infants and immunocompromised patients. However, RSV can also contribute to acute respiratory failure in adults, particularly among the elderly population. The objective of this study was to analyze the clinical characteristics and outcomes of immunocompetent adults hospitalized for RSV infection.

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Article Synopsis
  • Head and neck cancer significantly affects the quality of life (QoL) of older patients, with this study evaluating the impact of geriatric-assessment (GA)-based interventions on QoL over two years.
  • The study involved 475 patients aged 65 and older, comparing those who received a GA-driven intervention to those receiving standard care, using specific QoL questionnaires for measurement.
  • Results showed improvements in QoL scores overall, but no major differences between the intervention and control groups; most patients in the intervention group did not complete the full treatment, highlighting the need for better healthcare models tailored to patients' needs.
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