Medication underuse in real-life practice: the impact of galcanezumab towards achieving very low frequency episodic migraine in a southeast Asian middle-income nation.

Background: Migraine progression, particularly from episodic to chronic migraine (CM), increases disease burden and healthcare costs. Understanding the new concept of "Medication Underuse Headache" should encourage the health care provider to consider early intervention with calcitonin gene-related peptide (CGRP) monoclonal antibodies. Galcanezumab given early in the course of the disease, may prevent migraine chronification and have a robust response, moreso than when initiated in later stages of migraine.

Goals of care conversations and advance care planning for paediatric patients living with serious illness.

Goals of care discussions and advance care planning aim to align the values and wishes of patients and their families with the care received. All paediatric health care practitioners who care for fetuses, infants, children or adolescents with serious illnesses have an ethical responsibility to educate themselves about these aspects of care. This statement assists care providers with important conversations.

Les objectifs des échanges sur les soins et de la planification préalable des soins chez les patients d'âge pédiatrique atteints d'une maladie grave.

Les échanges sur les soins et la planification préalable des soins visent à faire concorder les valeurs et les désirs des patients et de leur famille avec les soins qu'ils reçoivent. Tous les professionnels de la santé qui soignent des fœtus, des nourrissons, des enfants ou des adolescents atteints de maladies graves ont la responsabilité éthique de s'éduquer à l'égard de ces aspects des soins. Le présent document de principes aide les professionnels de la santé à entamer ces discussions importantes.