Publications by authors named "A Ramondetta"
Introduction: Early psoriatic arthritis (PsA) diagnosis is critical to prescribe timely treatment to prevent the irreversible joint damage and the many other problems that patients with PsA experience. This retrospective study aimed to highlight the benefits of a Rheuma-Derma Clinic focused on the early diagnosis and prompt treatment of PsA with a shared approach among Italian psoriasis patients. Diagnosing PsA early is the main goal to reduce joint damage and disability in the patients affected.
View Article and Find Full Text PDFPurpose: Epidermal hyperplasia and the involvement of immune cells characterize the clinical picture of psoriasis. Among the several factors involved, attention has been focused on sirtuin 1 (SIRT1) - a deacetylase endowed with a variety of functions including the control of metabolic and inflammatory processes-, and on nicotinamide phosphoribosyltransferase (NAMPT), important for SIRT1 activation and involved in inflammatory events. The aim of the study was to analyze changes of SIRT1 and NAMPT expression in psoriatic skin.
View Article and Find Full Text PDFArticle Synopsis
- Scleroderma-like disorders are diverse conditions affecting skin, subcutaneous tissue, and sometimes muscle, resulting from various underlying mechanisms.
- *Differentiating these disorders from systemic sclerosis involves checking for the absence of antinuclear antibodies, Raynaud's phenomenon, and capillaroscopic changes.
- *Correct diagnosis depends on assessing the main affected areas, clinical progression, associated health issues, and distinct histological characteristics.*