Publications by authors named "A Ramalli"

Over the past decade, ultrasound microvasculature imaging has seen the rise of highly sensitive techniques, such as ultrafast power Doppler (UPD) and ultrasound localization microscopy (ULM). The cornerstone of these techniques is the acquisition of a large number of frames based on unfocused wave transmission, enabling the use of singular value decomposition (SVD) as a powerful clutter filter to separate microvessels from surrounding tissue. Unfortunately, SVD is computationally expensive, hampering its use in real-time UPD imaging and weighing down the ULM processing chain, with evident impact in a clinical context.

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Ultrasound open scanners have recently boosted the development and validation of novel imaging techniques. They are usually split into hardware- or software-oriented systems, depending on whether they process the echo data using embedded FPGAs/DSPs or a GPU on a host PC. The goal of this work was to realize a high-performance heterogeneous open scanner capable of leveraging the strengths of both hardware and software-oriented systems.

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In this study, we demonstrate that a deep neural network (DNN) can be trained to reconstruct high-contrast images, resembling those produced by the multistatic Synthetic Aperture (SA) method using a 128-element array, leveraging pre-beamforming radiofrequency (RF) signals acquired through the monostatic SA approach. : A U-net was trained using 27200 pairs of RF signals, simulated considering a monostatic SA architecture, with their corresponding delay-and-sum beamformed target images in a multistatic 128-element SA configuration. The contrast was assessed on 500 simulated test images of anechoic/hyperechoic targets.

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Brachial artery flow-mediated dilation (BAFMD) is induced by hyperemic wall shear rate (WSR) following forearm ischemia. In older adults, there appears to be a reduced brachial hyperemic WSR and altered stimulus-response relationship compared with young adults. However, it is unclear if an altered forearm microvascular response to ischemia influences brachial hyperemic WSR in older adults.

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Article Synopsis
  • The study investigated the effectiveness of a new ultrasound technique for imaging kidney blood vessels in pigs using a specialized device called a sparse spiral array.
  • Researchers used different microbubble concentrations and transmission sequences to capture detailed 3D images and assess blood flow in the kidneys, comparing their findings to results from a standard 2-D ultrasound.
  • The results showed that the new method successfully visualized kidney vasculature and blood flow, providing accurate and reliable data that matched traditional ultrasound results.
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