Publications by authors named "A Rajkumari"
Introduction: Nanotechnology may open up new avenues for overcoming the challenges of pancreatic cancer therapy as a broad arsenal of anticancer medicines fail to realize their full therapeutic potential in pancreatic ductal adenocarcinoma due to the formation of multiple resistance mechanisms inside the tumor. Many studies have reported the successful use of various nano formulations in pancreatic cancer therapy.
Areas Covered: This review covers all the major nanotechnology-based patent litrature available on renowned patent data bases like Patentscope and Espacenet, through the time period of 2007-2022.
Purpose: The study was done to measure the placental thickness (PT) in pregnant women and find its correlation with the gestational age (GA) of the fetus by ultrasonography. Comparisons were also made with the other fetal biometry parameters, and baseline data were generated with respect to the gestational weeks and placental position.
Materials And Methods: The study was a cross-sectional one with a sample size of 134 singleton pregnancies.
Objective: This investigation deals with the development and evaluation (in vitro and in vivo) of pH triggered Eudragit-coated chitosan microspheres of curcumin (CUR) for treating ulcerative colitis.
Methods: CUR-loaded chitosan microspheres were initially prepared by emulsion cross linking method followed by coating with Eudragit S-100. The pharmacodynamics of the developed formulation was analyzed in mice by acetic acid induced colitis model.
Article Synopsis
- The study tested the anti-inflammatory and antioxidant properties of methanol extract from Ruta graveolens leaves (RG-M) using both animal models and lab experiments.
- RG-M showed a significant reduction in inflammation markers, with up to 56.28% inhibition of edema and significant decreases in leukocyte migration and protein exudation.
- The extract also inhibited key enzymes related to inflammation and demonstrated strong antioxidant activity, indicating its potential benefits in managing inflammation and oxidative stress.
Enteric protozoal parasitic infection has become an important cause of morbidity in children and adults. In the developing countries the association of Cryptosporidium with acute and persistent diarrhoea has been striking. Stool samples from 1002 patients (800 adults and 202 children) suffering from diarrhoea or other gastrointestinal symptoms were examined for the presence of Cryptosporidium parvum oocysts by modified Ziehl Neelsen stained smears.
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