Significance of additive manufacturing amidst the pandemic.

In the light of COVID-19 pandemic, a global shortage for Personnel Protective Equipment (PPE) led to the search for an alternative to fill the gap where additive manufacturing made necessary development of rapid design and adaptive filtering masks for local manufacturing using 3D printing to help the frontline workers. The review focuses on the utilization of antimicrobial materials in additive manufacturing with the use of bespoke design to facilitate and respond to the disruptions in the medical supply chain. Previous studies confirmed the age-old theory of copper as an antimicrobial material with contact killing properties.

Intraoperative diagnosis of glioblastomamultiforme with oligodendroglial and sarcomatous components.

Glioblastoma, the most frequent primary brain tumor and the most malignant neoplasm, can have the most heterogeneous morphological presentation. Along with classical morphological features, areas of oligodendroglial component and mesenchymal differentiation may be seen. The present case was a rare case of glioblastoma presenting with sarcomatous and oligodendroglial components.

Mutation analysis of the KIF21A gene in an Indian family with CFEOM1: implication of CpG methylation for most frequent mutations.

Purpose: To carry out the mutation analysis of the KIF21A gene in a four-generation Indian family affected with CFEOM1 and to find out the molecular basis of the most frequent mutations c.2860C>T and c.2861G>A in exon 21 of the KIF21A gene.