[Inoperable non-small-cell bronchial carcinoma: macroscopic and microscopic tumor behavior during and after radiotherapy with curative intent].

The supervision of the efficacy of therapy with curative aim in inoperable NSCLC focus on clinical and radiological parameters and the survival rate. But the decision about the local tumour elimination lies in the microscopic area, which cannot be controlled neither by laboratory tests nor by radiological examinations. About twenty years ago with support of our pneumologist we carried out bronchoscopies and biopsies depending on the applied radiation dose.

[Local efficiency of percutaneous radiotherapy in lung cancer. Analysis of 215 repeated bronchoscopies in relation to applied radiation dosage].

Purpose: During a locoregional radiotherapy with curative attempts of lung cancer patients bronchoscopic examinations with biopsies and/or cytologic lavages were repeated to assess the accuracy of limiting the total dose to 60 Gy. In order of the applied dose macroscopic changements of the endoluminal tumor and microscopic elimination should be made out. The correlation between macro- and microscopical regression should allow a statement about reliability of single results.

[Acute dyspnea, cough, headache].

Six hours after work in an empty, non-ventilated silo a 27-year-old Yugoslav worker suffered acutely from cough, dyspnea and general weakness. He was admitted to the hospital with severe partial respiratory insufficiency, and after emergency intubation artificial respiration had to be installed. X-ray showed a severe symmetrical alveolo-interstitial opacity.

[Acute effects of the natural atmospheric ozone exposure on lung function of clinically normal smokers and non-smokers].

The influence of moderate ambient ozone exposure on spirometric lung function and bronchial responsiveness was analyzed in 13 healthy adult nonsmokers and 11 asymptomatic smokers. The study was divided into an initial investigation at low atmospheric ozone concentrations of about 80 (range 68-102) micrograms/m3 and a subsequent similar testing at moderately elevated ozone concentrations above 140 (range 145-205) micrograms/m3. Overall there was a slight but significant impairment in forced expiratory volumes (p less than 0.