Publications by authors named "A R Theile"

Article Synopsis
  • Hypersensitivity pneumonitis (HP) is an uncommon lung allergy primarily caused by inhaling organic dusts, with rare instances linked to chemicals like phthalates found in plastics.
  • A clinical case involving a cable production worker demonstrated that symptoms initially diagnosed as idiopathic pulmonary fibrosis were linked to chronic HP resulting from exposure to phthalates, confirmed by specific IgG antibodies and other clinical findings.
  • The study highlights the need for greater awareness of phthalates as potential triggers for occupational HP, as it has not been commonly recognized in previous case reports.
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[Benign mesothelial tumors].

Pathologie (Heidelb)

September 2024

Benign mesothelial tumors are rarer than malignant mesotheliomas and are often found in the peritoneum as incidental findings in women. They include the adenomatoid tumor (AT), the well-differentiated mesothelial tumor (WDPMT), the mesothelioma in situ (MIS), and the solid papillary mesothelial tumor (SPMT). ATs are always benign and predominantly manifest in the genital tract.

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Objective: To determine the adherence and safety outcomes of a 5-day antibiotic course with a "time-out" for treatment of "blood culture-negative" pneumonia in the NICU.

Study Design: Prospective surveillance of all infants diagnosed with pneumonia at 7 NICUs from 8/2020-12/2021. Safety outcomes were defined a priori by re-initiation of antibiotic therapy within 14 days after discontinuation and overall and sepsis-related mortality.

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Objective: On 2/2019, the Neonatal Antimicrobial Stewardship Program at Nationwide Children's Hospital recommended reducing empirical antibiotic therapy for early-onset sepsis (EOS) from 48 to 24 hours with a TIME-OUT. We describe our experience with this guideline and assess its safety.

Methods: Retrospective review of newborns evaluated for possible EOS at 6 NICUs from 12/2018-7/2019.

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