Survival of Mesenchymal Stem Cells in Different Methods of Nebulization.

We compared survival of bone marrow mesenchymal stem cells after compressor, ultrasound, and mesh nebulization of the cell suspension over 10 min. Viability of stromal cells was best preserved after compressor nebulization (72%). Cell survival after ultrasonic nebulization was significantly lower (20%).

[The results of the combined programmed treatment of those who cleaned up the accident at the Chernobyl Atomic Electric Power Station who suffer from respiratory organ diseases].

Examination of respiratory system in subjects exposed to long-term inhalation of radioactive dust when engaged in repair works after the Chernobyl accident have revealed specific pathology of the respiratory organs caused by long-term persistence of radioactive dust in the lung tissue. A special regimen of combined treatment has been developed which included: bronchoalveolar lavage, antioxidants, broncholytics, mucolytics, extracorporeal procedures, physical rehabilitation. 1-year monitoring of subjects on this treatment versus untreated controls proved the above regimen beneficial as the patients exhibited less intensive clinical symptoms, less frequent exacerbations of infectious and inflammatory processes, higher quality of life.

[Respiratory and hemodynamic disorders in the participants in the cleanup of the aftermath of the accident at the Chernobyl Atomic Electric Power Station].

After examination of cardiorespiratory function in 10 males exposed to Chernobyl accident unfavorable factors at the age of 31-45 years suffering from chronic obstructive bronchitis (7 cases) and mixed bronchial asthma (3 cases) it was established that the patients had ventilation disorders of mixed genesis (moderate obstructive and respiratory affections), frequently occurring decreased specific diffusion (DLCO/Va) in normal total diffusion capacity of the lungs, inefficient gas exchange, midly declined left ventricular pump capacity and contractility. In the above patients a relationship was found between parameters of central hemodynamics assessed at echo-CG and severity of ventilation impairment and respiratory insufficiency.

[Respiratory organ pathology in the participants in the cleanup of the accident at the Chernobyl Atomic Electric Power Station].

The authors performed this investigation to ascertain the role of radioactive dust inhalation in the onset of respiratory diseases and determination of clinicomorphological features of such pathology. The authors have found that work in conditions of massive dust exposure, stay in the dust zone for a month and longer in 1986-1987 were the decisive risk factors of respiratory impairment. The examination covered 28 patients who had acute symptoms of inhalation damage to respiratory system when performing their job in the contaminated zone.

[The morphological properties of the blood thrombocytes in bronchial asthma patients before and after thrombocytapheresis].

Morphological characteristics of platelets were assessed electron microscopically in 15 patients with atopic and aspirin bronchial asthma (BA) before and after thrombocytapheresis (TA). All the patients had a definite shift of platelet subpopulations to greater percentage of spherical forms as well as defects in cell ultrastructure. This makes evident platelet activation in patients with BA aggravation.