Transport Properties of a Half-Filled Chern Band at the Electron and Composite Fermion Phases.

We consider a half-filled Chern band and its transport properties in two phases that it may form: the electronic Fermi liquid and the composite-fermion Fermi liquid. For weak disorder, we show that the Hall resistivity for the former phase is very small, while for the latter it is close to 2h/e^{2}, independent of the distribution of the Berry curvature in the band. At rising temperature and high frequency, we expect the Hall resistivity of the electronic phase to rise, and that of the composite-fermion phase to deviate from 2h/e^{2}.

Navigating a fine balance: point-mutant cheater viruses disrupt the viral replication cycle.

Cheater viruses cannot replicate on their own yet replicate faster than the wild type (WT) when the two viruses coinfect the same cell. Cheaters must possess dual genetic features: a defect, which leads to their inability to infect cells on their own, and a selective advantage over WT during co-infection. Previously, we have discovered two point-mutant cheaters of the MS2 bacteriophage.

Letermovir for prevention of recurrent CMV in high-risk allogeneic hematopoietic cell transplant (HCT) recipients.

Background: We evaluated letermovir (LTV) for secondary prophylaxis for cytomegalovirus (CMV) in allogeneic hematopoietic cell transplant recipients (HCT) at high-risk for CMV recurrence.

Methods: Open-label study conducted at Memorial Sloan Kettering Cancer Center and the University of Minnesota. Patients with clinically significant CMV infection (cs-CMVi) and ≥1 high-risk criteria for CMV who achieved viral suppression with standard CMV antivirals, received letermovir (LTV) secondary prophylaxis for up to 14 weeks.

Nano spray-dried particles of in-situ crosslinked alginate and their toxicological characterisation.

The feasibility and technical capacity for producing crosslinked sub-micron gels with a nano spray-dryer were studied with variable pH systems incorporating alginate, pectin, and pullulan. The obtained powders were characterized for their morphology, particle size distribution, and their toxicological safety profile using genotoxicity and cytotoxicity assays. Additionally, quercetin was added to the encapsulation system to study the potential of the system to encapsulate this material.