Publications by authors named "A R Shimotake"

Purpose: Magnetization prepared rapid gradient echo (MPRAGE) is a useful three-dimensional (3D) T1-weighted sequence, but is not a priority in routine brain examinations. We hypothesized that converting 3D MRI localizer (AutoAlign Head) images to MPRAGE-like images with deep learning (DL) would be beneficial for diagnosing and researching dementia and neurodegenerative diseases. We aimed to establish and evaluate a DL-based model for generating MPRAGE-like images from MRI localizers.

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  • The study compared EEG findings in patients with Alzheimer's disease (AD) versus dementia with Lewy bodies (DLB) and Parkinson's disease with dementia (PDD) to identify differences in brain activity patterns.
  • Visual analysis showed that patients with DLB/PDD had a lower posterior dominant rhythm (PDR) frequency and certain EEG patterns strongly indicated DLB/PDD while ruling out AD.
  • Both visual and automated EEG analyses yielded similar results regarding PDR, demonstrating that visual assessment effectively distinguishes between AD and DLB/PDD, with automated analysis acting as a supportive tool, particularly for Parkinson's-related dementia.
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  • This study revisits the basal temporal language area (BTLA) using electrical cortical stimulation (ECS) to analyze its role in the Japanese language among 11 patients with focal epilepsy.
  • It creates a functional density map highlighting the BTLA's anatomical features and found that spoken-word tasks were more affected by ECS than reading tasks, indicating different levels of language processing.
  • The findings suggest a functional gradient in the BTLA, with the front involved in broader semantic processing and the back, particularly the middle fusiform gyrus, focused on specific types of input.
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Objective: Degree of indication for epilepsy surgery is determined by taking multiple factors into account. This study aimed to investigate the usefulness of the Specific Consistency Score (SCS), a proposed score for focal epilepsy to rate the indication for epilepsy focal resection.

Methods: This retrospective cohort study included patients considered for resective epilepsy surgery in Kyoto University Hospital from 2011 to 2022.

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Objective: Postseizure functional decline is a concern in poststroke epilepsy (PSE). However, data on electroencephalogram (EEG) markers associated with functional decline are scarce. Thus, we investigated whether periodic discharges (PDs) and their specific characteristics are associated with functional decline in patients with PSE.

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