Publications by authors named "A R Schned"
Article Synopsis
- The study aims to identify new genetic variants that increase the risk of bladder cancer using data from 32 studies involving 13,790 patients and 343,502 control subjects of European descent.
- Researchers discovered multiple novel susceptibility loci and enhanced signals in known regions, achieving a total of 24 significant markers linked to bladder cancer risk.
- The findings indicate that the risk is further influenced by factors such as sex and smoking status, with a polygenic risk score showing a significant difference in lifetime risk for bladder cancer based on genetic predisposition.
Background: Recent studies indicate that bladder cancer is among the top 10 most common cancers in the world (Saginala et al. 2022). Bladder cancer frequently reoccurs, and prognostic judgments may vary among clinicians.
View Article and Find Full Text PDFPurpose: We examined the interaction between common genetic bladder cancer variants, diet quality, and bladder cancer risk in a population-based case-control study conducted in New England.
Methods: At the time of enrollment, 806 bladder cancer cases and 974 controls provided a DNA sample and completed a diet history questionnaire. Diet quality was assessed using the 2010 Alternate Healthy Eating Index (AHEI-2010) score.
Nutrition may impact bladder cancer survival. We examined the association between diet quality and overall and bladder cancer-specific survival. Bladder cancer cases from a population-based study reported pre-diagnosis diet.
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