Publications by authors named "A R O'Hagan"
The UK Biobank (UKB) is a large cohort study that recruited over 500,000 British participants aged 40-69 in 2006-2010 at 22 assessment centers from across the United Kingdom. Self-reported health outcomes and hospital admission data are 2 types of records that include participants' disease status. Coronary artery disease (CAD) is the most common cause of death in the UKB cohort.
View Article and Find Full Text PDFBackground: Little research has been completed on the correlation between cystic fibrosis (CF) modulator therapy and its effect on respiratory cultures in CF patients. This study evaluated the effect of elexacaftor/tezacaftor/ivacaftor (ETI) on respiratory colonization with Pseudomonas aeruginosa.
Methods: This single center, IRB approved, retrospective chart review compared patient data two years immediately prior to ETI initiation with patient data two years post-initiation from January 2017-December 2022.
Article Synopsis
- Human memory is impacted by sleep, but the relationship between sleep and false memory (remembering things that never happened) is less understood, particularly in the context of the Deese-Roediger-McDermott (DRM) paradigm.* -
- A recent study tested how sleep influences false memories, finding that while sleep participants had fewer incorrect memories overall, they often recalled more related but incorrect words (critical lures) compared to participants who stayed awake.* -
- The results suggest a complex relationship between sleep and false memory that doesn't fit neatly into existing theories, indicating that sleep may help both in enhancing relevant memories and in suppressing irrelevant ones.*
Background And Aim: We examined error-driven learning in fMRI activity of 217 subjects in a stop signal task to obtain a more robust characterization of the relation between behavioral measures of learning and corresponding neural learning signals than previously possible.
Methods: The stop signal task is a two-alternative forced choice in which participants respond to an arrow by pressing a left or right button but must inhibit that response on 1 in 7 trials when cued by an auditory "stop signal." We examined post-error learning by comparing brain activity (BOLD signal) and behavioral responses on trials preceded by successful (correct stop) vs.