Publications by authors named "A R Niang"
Preoperative mortality risk evaluation in abdominal surgical emergencies: development and internal validation of the NDAR score from a national multicenter audit in Senegal.
BMC Surg
October 2024
Introduction: Abdominal surgical emergencies have a high mortality rate. Effective management primarily relies on the early identification of patients at high risk of postoperative complications. The objective of our study was to determine the prognostic factors associated with poor outcomes from abdominal surgical emergencies in Senegal and to establish a predictive score for mortality for preoperative risk evaluation (NDAR (New Death Assessment Risk) score).
View Article and Find Full Text PDFCohesin shapes the chromatin architecture, including enhancer-promoter interactions. Its components, especially STAG2, but not its paralog STAG1, are frequently mutated in myeloid malignancies. To elucidate the underlying mechanisms of leukemogenesis, we comprehensively characterized genetic, transcriptional, and chromatin conformational changes in acute myeloid leukemia (AML) patient samples.
View Article and Find Full Text PDFArticle Synopsis
- Cholera, caused by the bacteria Vibrio cholera, poses a significant public health risk in Africa; this study aimed to examine pathogenic Vibrionaceae in human stool and environmental water samples from Saint-Louis, Senegal.
- A hospital-based study from 2013 to 2015 involved collecting stool samples and conducting monthly water testing to identify Vibrio bacteria using PCR techniques.
- The results showed no V. cholerae strains in patients' stool, but various Vibrio species, including toxigenic ones, were found in water, highlighting potential environmental risks for Vibriosis transmission in the region.*
Article Synopsis
- Integrated kidney care connects preventative measures for chronic kidney disease with health services for those already affected, focusing on smooth transitions between different stages of the disease and treatment options.
- Supportive care is crucial for individuals with kidney failure, yet it is often lacking or poorly integrated, particularly in low- and middle-income countries where resources are limited.
- The International Society of Nephrology has developed consensus definitions and guidelines to improve the understanding and implementation of conservative kidney management and supportive care in these under-resourced settings.