Publications by authors named "A R NICOL"

Background: A number of UK transplantation centres use isotope studies to estimate the relative contribution from each kidney in living kidney donor assessment. The evidence that the estimation of pre-donation split function of the non-donated kidney influences post-donation renal recovery is limited. The aim of this study was to analyse whether, in the context of other donor factors, the split function of the non-donated kidney predicts the percentage recovery of glomerular filtration rate (GFR) at one-year post-donation.

View Article and Find Full Text PDF
Article Synopsis
  • Oral mucositis (OM) is a significant complication for nasopharyngeal carcinoma (NPC) patients undergoing radiotherapy, impacting their quality of life, and this study aimed to create a prediction model for severe OM.
  • The research involved 464 NPC patients, with a focus on developing a multi-omic model that incorporated clinical, radiomic, and dosiomic features and comparing its effectiveness to a conventional model.
  • The multi-omic approach demonstrated better predictive accuracy for severe OM, highlighting the potential for personalized treatment strategies in managing this debilitating side effect in NPC patients.
View Article and Find Full Text PDF

Hepatitis E virus (HEV) is a globally distributed pathogen that causes acute hepatitis in people. Recent human cases of HEV arising after contact with urban rats (Rattus spp.) have raised concerns regarding whether rats may be a source of HEV infection.

View Article and Find Full Text PDF

Nitrogen (N) fertilization in paddy soils decreases arsenic mobility and methane emissions. However, it is unknown how quantity and frequency of N fertilization affects the interlinked redox reactions of iron(II)-driven denitrification, iron mineral (trans-)formation with subsequent arsenic (im-)mobilization, methane and nitrous oxide emissions, and how this links to microbiome composition. Thus, we incubated paddy soil from Vercelli, Italy, over 129 days and applied nitrate fertilizer at different concentrations (control: 0, low: ∼35, medium: ∼100, high: ∼200 mg N kg soil) once at the beginning and after 49 days.

View Article and Find Full Text PDF