Publications by authors named "A R MEJIA"
Flexor tendon injuries are a commonly encountered hand problem caused by trauma. They can be associated with fractures or neurovascular injury or occur in isolation. Thorough physical examination is an integral aspect of management of these injuries to identify concomitant pathology and to facilitate preoperative planning and timing of surgery to improve outcome.
View Article and Find Full Text PDFBackground: Castleman disease (CD) is a rare lymphoproliferative disorder, with intracranial involvement being exceedingly rare. Unicentric Castleman disease (UCD) is typically benign and localized, but its presentation can mimic other intracranial pathologies, complicating diagnosis.
Case Description: We reported a 52-year-old woman who presented with progressive headaches and language disturbances.
On September 29, 2023, the Republic of Ecuador convened a meeting to address surgical system strengthening and urge political leaders to invest in surgical infrastructure. The meeting included experts in health diplomacy, innovative financing, implementation strategy and national surgical plans. The event occurred in parallel with the Sixtieth Directing Council of the Pan American Health Organization, Seventy-fifth session of the World Health Organization Regional Committee for the Americas.
View Article and Find Full Text PDFBackground: As liver metastasis is the most common cause of mortality in patients with colorectal cancer, studying colorectal cancer liver metastasis (CLM) microenvironment is essential for improved understanding of tumor biology and to identify novel therapeutic targets.
Methods: We used a multiplex immunofluorescence platform to study tumor associated macrophage (TAM) polarization and adaptive T cell subtypes in tumor samples from 105 CLM patients (49 without and 56 with preoperative chemotherapy).
Results: CLM exhibited M2 macrophage polarization, and helper T cells were the prevalent adaptive T cell subtype.
Article Synopsis
- Cardiac pressure overload can lead to problems for patients with congenital heart defects, and using stem cell-derived heart cells might help improve heart function alongside surgery.
- Researchers successfully implanted human stem cell-derived heart cells into the hearts of rhesus macaques facing induced pressure overload, achieving good integration with the existing heart tissue.
- Although some monkeys experienced episodes of ventricular tachycardia after the cell transplant, these events generally resolved within a few weeks, indicating a need for monitoring but also promising potential for this treatment approach.