Publications by authors named "A R Light"
Objectives: The objective of this study is to compare the early oncological outcomes of delayed (>90 days) versus scheduled (≤90 days) radical prostatectomy (RP).
Patients And Methods: Patients with prostate cancer due to undergo surgery between March 2020 and June 2020 who were enrolled in the COVIDSurg-Cancer international, observational study were prospectively followed up for 1 year. Time to surgery was defined as the difference between the operation date and the multi-disciplinary team decision to offer surgery.
Article Synopsis
- Radical prostatectomy (RP) is a key surgical treatment for prostate cancer, but assessing surgical margins during the procedure is difficult and costly, making fluorescence confocal microscopy (FCM) a potential solution.
- The IP8-FLUORESCE study is a multicentre, prospective study that investigates the accuracy of digital FCM in identifying prostate cancer at surgical margins, comparing it to traditional histopathology methods.
- The study will involve 153 patients undergoing robot-assisted RP, using FCM on prostate specimens immediately after surgery, with results evaluated by blinded uro-pathologists for accuracy in detecting cancer presence at the margins.
Objective: The objective of this study was to report the 12-month oncological outcomes for patients with non-muscle-invasive bladder cancer (NMIBC) within the prospective, international COVIDSurg Cancer study.
Patients And Methods: Eligible patients were aged ≥18 years and scheduled for elective surgical management of NMIBC with curative intent (transurethral resection of bladder tumour [TURBT] or bladder biopsy) from 21 January to 14 April 2020. The primary outcome was disease recurrence within 12 months of previous elective TURBT/bladder biopsy.
Endothelial cells are integral components of all vasculature within complex organisms. As they line the blood vessel wall, endothelial cells are constantly exposed to a variety of molecular factors and shear force that can induce cellular damage and stress. However, how endothelial cells are removed or eliminate unwanted cellular contents, remains unclear.
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