Publications by authors named "A R Hamzeh"

The lipoxygenase (LOX) activity of major tropical fish used for surimi production, including threadfin bream (TB), lizardfish (LZ), and goatfish (GF), was measured in the gills, skin, and muscle. The highest LOX activity was observed in the LZ samples (p < 0.05), with the gills exhibiting the greatest activity at 376.

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Antibacterial peptides from black soldier fly larvae extract were prepared using Flash column chromatography. Three out of five fractions (F, F and F) showed antibacterial activity against Listeria monocytogenes DMST 17303 with a minimum inhibitory concentration (MIC) of 1 mM, followed by Salmonella enterica Enteritidis DMST 15679 and Escherichia coli O157:H7 DMST 12743 with a MIC ranging from 4 to 8 mM. Due to the higher yield, F and F were further analyzed on their mode of action against L.

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The study examined the antihypertensive effect of peptides derived from pepsin-hydrolyzed corn gluten meal, namely KQLLGY and PPYPW, and their in silico gastrointestinal tract digested fragments, KQL and PPY, respectively. KQLLGY and PPYPW showed higher angiotensin I-converting enzyme (ACE)-inhibitory activity and lower ACE inhibition constant (K) values when compared to KQL and PPY. Only KQL showed a mild antihypertensive effect in spontaneously hypertensive rats with -7.

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Physico-chemical behaviors of natural actomyosin (NAM) from slow-growing Korat chicken (KC) breast and thigh at low (0.2 M) and high (0.6 M) NaCl concentrations were evaluated and compared to those from their corresponding muscles in fast-growing broiler chicken (BC).

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Article Synopsis
  • LCP1 is a gene that encodes L-plastin, an actin-bundling protein important for immune cells, and its deficiency can lead to various blood and immune issues in mice and fish.
  • This study investigated a specific genetic variant of LCP1 found in humans that was linked to an inherited immune deficiency, using genetic and cellular analysis on affected family members as well as engineered mouse and cell models.
  • Results showed that the identified genetic mutation causes significant blood cell reductions and functional defects, highlighting a unique immune disorder marked by issues in neutrophils, lymphocytes, and platelets due to partial LCP1 deficiency.
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