Short-interval recanalization after gelfoam occlusion.

Gelfoam® is a temporary embolization agent often used in trauma where permanent arterial occlusion is not desired. Gelfoam occlusions have been shown to resolve by 2 weeks, but shorter intervals have not been studied. We report a case of spontaneous arterial hemorrhage due to ruptured hepatic malignancy where treatment was Gelfoam slurry occlusion of the right hepatic artery.

Activation of stem cell up-regulation/mobilization: a cardiovascular risk in both mice and humans with implications for liver disease, psoriasis and SLE.

Experimentally induced injury triggers up-regulation and mobilization of stem cells in mice that causes accelerated atherosclerosis. mice have chronic activation of stem cell up-regulation/mobilization and accelerated atherosclerosis. In addition, the mice have elevation of serum cytokines G-CSF, IL-17 and IL-23, each necessary for stem cell mobilization.

Hypersplenism in liver disease and SLE revisited: current evidence supports an active rather than passive process.

Background: Active and passive theories have been advanced to explain splenomegaly and cytopenias in liver disease. Dameshek proposed active downregulation of hematopoiesis. Doan proposed passive trapping of blood components in a spleen enlarged by portal hypertension.