A comprehensive review of sustainable hydrogels from lignin for advanced wastewater solutions.

Throughout the recent years, water bodies have been significantly contaminated via various industrial and pollution wastes posing threats to the living. To tackle the situation, Lignin-Based Hydrogels have appeared as a material with great potential for wastewater treatment. Biomass-derived polymers for wastewater treatment present a sustainable replacement to plastics based on petroleum owing to its biocompatibility, affordability, eco-friendliness and biodegradability.

Third molar assessment for legal age determination in Indonesian juveniles using Demirjian method.

Third molar radiographic assessment can help determine the probability of an individual reaching the legal age of majority, typically 18 years old. This study aims to assess this probability using third molar development through the Demirjian staging system. The sample consisted of 429 panoramic radiographs (210 females, 219 males) from individuals aged 15-23.

Prevalence of ABO, Rh (D, C, c, E, and e), and Kell (K) antigens in blood donors: A single-center study from South India.

Background: Although ABO and RhD are the clinically significant blood group antigens that are routinely tested for, other blood group antigens may become important in multiply transfused patients due to risk of alloimmunization. Knowledge of antigen prevalence in a population is important in the context of alloimmunization and antigen matching. This study aims to do the same in a population of voluntary blood donors of a center in South India.

In Silico design and molecular dynamics analysis of imidazole derivatives as selective cyclooxygenase-2 inhibitors.

Cyclooxygenase-2 (COX-2), a key enzyme in the inflammatory pathway, is the target for various nonsteroidal anti-inflammatory drugs (NSAIDs) and selective inhibitors known as coxibs. This study focuses on the development of novel imidazole derivatives as COX-2 inhibitors, utilizing a Structure-Activity Relationship (SAR) approach to enhance binding affinity and selectivity. Molecular docking was performed using Autodock Vina, revealing binding energies of -6.

A Novel In Vitro Model of the Bone Marrow Microenvironment in Acute Myeloid Leukemia Identifies CD44 and Focal Adhesion Kinase as Therapeutic Targets to Reverse Cell Adhesion-Mediated Drug Resistance.

Background/objectives: Acute myeloid leukemia (AML) is an aggressive neoplasm. Although most patients respond to induction therapy, they commonly relapse due to recurrent disease in the bone marrow microenvironment (BMME). So, the disruption of the BMME, releasing tumor cells into the peripheral circulation, has therapeutic potential.