Publications by authors named "A R Cuff"
Liver ischaemia-reperfusion (IR) injury remains a major cause of morbidity and mortality following liver transplantation and resection. CD4+ T cells have been shown to play a key role in murine models; however, there is currently a lack of data that support their role in human patients. Data on clinical outcomes and complications were documented prospectively in 28 patients undergoing first elective liver transplant surgery.
View Article and Find Full Text PDFIntroduction: Wastewater surveillance is an important technique to monitor public health and is being studied extensively for pandemic prevention, force health protection and readiness, and as a potential early warning system for chem-bio defense. Wastewater surveillance has traditionally relied on techniques such as quantitative PCR or targeted sequencing, both of which are microbe- or disease-specific tools. Newer pan-viral metagenomics strategies may provide higher specificity for pathogens of interest, resulting in a lower false negative rate and reduced sequencing of undesired background nucleic acids.
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- Advanced Practice Physiotherapists (APPs) increasingly use MRI to diagnose lumbosacral radiculopathy (LSR) and rule out other spinal issues, but there's limited data on how their assessments correlate with MRI findings.
- The study analyzed the diagnostic and treatment plan differences pre- and post-MRI for 482 patients, revealing significant correlations between APP diagnoses and MRI results.
- Findings indicate a weak but statistically significant correlation between pre- and post-MRI treatment plans, suggesting APP diagnoses align somewhat with MRI outcomes, though the impact on treatment may vary.
Endometriosis negatively impacts the health-related quality of life of 190 million women worldwide. Novel advances in nonhormonal treatments for this debilitating condition are desperately needed. Macrophages play a vital role in the pathophysiology of endometriosis and represent a promising therapeutic target.
View Article and Find Full Text PDFBackground: Physiotherapists in the United Kingdom (UK), who have received additional training can adopt injection therapy for the treatment of musculoskeletal (MSK) disorders.
Objectives: The objective of this practice survey was to explore (i) the frequency of use of injection therapy by UK physiotherapists for MSK disorders; and (ii) the clinical reasoning for selection of injectate, dose and pre/post injection practice.
Design: Cross-sectional online survey.