Publications by authors named "A R Butnariu"
Article Synopsis
- Vascular complications after anterior cervical spine surgery, while rare, can lead to serious issues for patients, such as cerebral infarction, emphasizing the need for risk factor screening prior to surgery.
- A case study is presented where a patient developed symptoms like Horner syndrome post-surgery, followed by left hemiplegia due to ischemia in the right middle cerebral artery territory, leading to a complex emergency intervention.
- Despite the patient having no previous medical issues, tests revealed dyslipidemia, suggesting that pre-surgical ultrasound assessments of cervical arteries could help identify patients at higher risk for serious complications.
The blood-brain barrier (BBB) presents a formidable challenge in delivering therapeutic agents to the central nervous system. Ultrasound-mediated BBB disruption has emerged as a promising non-invasive technique to enhance drug delivery to the brain. This manuscript reviews fundamental principles of ultrasound-based techniques and their mechanisms of action in temporarily permeabilizing the BBB.
View Article and Find Full Text PDFIn this review, we reveal the latest developments at the interface between SARS-CoV-2 and the host cell surface. In particular, we evaluate the current and potential mechanisms of binding, fusion and the conformational changes of the spike (S) protein to host cell surface receptors, especially the human angiotensin-converting enzyme 2 (ACE2) receptor. For instance, upon the initial attachment, the receptor binding domain of the S protein forms primarily hydrogen bonds with the protease domain of ACE2 resulting in conformational changes within the secondary structure.
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- Cancer immunotherapy uses the body's immune system to target and kill cancer cells, unlike traditional methods like surgery and chemotherapy that are non-specific.
- It faces challenges such as immune suppression from the tumors and potential adverse side effects from treatments.
- New therapies like anti-cathepsin antibodies and galectin-1 blockade are currently being researched to enhance immune responses against tumors and improve treatment effectiveness.
Evaluation of Leaf Consumption and Determination of Economic Injury Level Caused by Plutella xylostella (L.) (Lepidoptera: Plutellidae) in Brassica oleracea var. acephala (Brassicales: Brassicaceae).
J Econ Entomol
August 2019
Plutella xylostella (L.) is a microlepidopteran found in all brassica-producing regions of the world. However, no economic injury level (EIL) has been established for this pest in collard greens.
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