Publications by authors named "A R Atti"

Background: Healthcare workers were at a high risk of infection early in the SARS-CoV-2 pandemic. It is uncertain to what extent occupational, household and community factors contributed, and how this changed over time. We aimed to characterise the risk factors for infection over four successive waves of the pandemic in a large, UK healthcare worker cohort (SIREN).

View Article and Find Full Text PDF
Article Synopsis
  • The study assessed the effectiveness of bivalent and monovalent mRNA COVID-19 boosters among UK healthcare workers from October 2023 to March 2024 during the circulation of the XBB.1.5 and JN.1 variants.
  • Among 2867 participants, about half received a booster, and 19% experienced confirmed infections; the monovalent booster showed better effectiveness compared to the bivalent one, especially in the first two months post-vaccination.
  • Results indicated that recent infections boosted immunity, and the findings suggest that tailored vaccines for circulating variants could be beneficial for seasonal immunization among healthcare workers.
View Article and Find Full Text PDF

Introduction: Following SARS-CoV-2 infection, some patients experience a range of long-lasting symptoms, with a specific burden on their lives and ability to work.

Aim: We describe the prevalence and impact of persistent symptoms pre-/post-vaccination in SIREN study participants.

Methods: A cross-sectional study of SARS-CoV-2 positive participants was carried out within SIREN, a frequently tested UK healthcare worker cohort with vaccination and demographic data available.

View Article and Find Full Text PDF

Introduction: Anorexia Nervosa (AN) is a complex psychiatric illness, characterized by a high risk of developing cardiovascular complications. Given the high risk of vascular diseases in patients with AN, we can assume that patients with severe AN have a high risk of developing ischemic stroke. However, to the best of our knowledge, no reports of patients with AN presenting with ischemic stroke have been published, other than a report of the development of IS during refeeding therapy in patients with severe AN.

View Article and Find Full Text PDF