Lipoic acid improves wound healing through its immunomodulatory and anti-inflammatory effects in a diabetic mouse model.

Objectives: Diabetes mellitus is a chronic disease that has become more prevalent worldwide because of lifestyle changes. It leads to serious complications, including increased atherosclerosis, protein glycosylation, endothelial dysfunction, and vascular denervation. These complications impair neovascularization and wound healing, resulting in delayed recovery from injuries and an elevated risk of infections.

Fezolinetant's efficacy and safety in treatment of vasomotor symptoms in postmenopausal women: a meta-analysis and GRADE evaluation of randomized controlled trials.

Background: Postmenopausal women are more likely to experience vasomotor symptoms (VMS), such as heat sensation and sweating. Recent trials have investigated fezolinetant in the treatment of VMS in postmenopausal women. Our study aims to conduct a meta-analysis of these trials in order to estimate fezolinetant's effectiveness and safety in the management of VMS in postmenopausal women.

Hyoid bone-based sex discrimination among Egyptians using a multidetector computed tomography: discriminant function analysis, meta-analysis, and artificial intelligence-assisted study.

The hyoid bone has been identified as sexually dimorphic in various populations. The current study is a forerunner analysis that used three-dimensional multidetector computed tomography (3D MDCT) images of the hyoid bone to examine sexual dimorphism in the Egyptian population. A total of 300 subjects underwent neck CT imaging, with an additional 60 subjects randomly selected for model validation.

Ultrasonographic assessment of optic nerve: does it help in lupus-induced optic neuropathy?

Objective: Evaluating the potential role of neuromuscular ultrasonography (NMUS) in assessing optic nerve affection in patients with systemic lupus erythematosus (SLE), compared with healthy controls and other conventional strategies in diagnosing optic neuropathy.

Methods: We conducted an observational cross-sectional study comparing patients with SLE and a healthy group. We measured the optic nerve diameter (OND) and optic nerve sheath diameter (ONSD) and calculated the OND/ONSD ratio and side-to-side difference.

Unraveling Chemical Profile, Antioxidant, Antialzheimer and Antimicrobial Potentials of Three Propolis from Northeastern Regions of Algeria: In Vitro and in Silico Evaluation.

This study investigates the pharmaceutical potential both in vitro and in silico of ethanolic propolis extract from three Algerian regions namely TAH (Tahir-Jijel), ATH (Oued Athmania-Mila) and OZ (Oued Zhor-skikda). Twenty-three compounds were identified via HPLC‒DAD, with key constituents including caffeic acid, cynarin, chrysin, naringin, and hesperetin. Moreover, Antioxidant and anti-Alzheimer activities were assessed by multiple assays.