Publications by authors named "A Q Guimaraes"

Background: Temporomandibular disorder (TMD) involves various conditions affecting the anatomy and functional characteristics of the temporomandibular joint (TMJ). Hence, this study evaluated pain perception and morbidity after dental implant surgeries in patients with and without TMD.

Material And Methods: It is a prospective randomized clinical trial with 50 participants with and without TMD, randomly selected for rehabilitation procedures with dental implants.

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The development of COVID-19 vaccines has been an important step in the fight against the pandemic. However, it is still necessary to understand the influence of factors that can alter the immune response. In general, doses need to be updated frequently, and care must be taken to control the virus that is still circulating worldwide.

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Patients with metastatic pancreatic ductal adenocarcinoma survive longer if disease spreads to the lung but not the liver. Here we generated overlapping, multi-omic datasets to identify molecular and cellular features that distinguish patients whose disease develops liver metastasis (liver cohort) from those whose disease develops lung metastasis without liver metastases (lung cohort). Lung cohort patients survived longer than liver cohort patients, despite sharing the same tumor subtype.

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Article Synopsis
  • Animal models are essential for scientific research, helping to uncover the mechanisms behind many human conditions.
  • The ethical implications of using animals in experiments remain a significant debate among scientists and the public.
  • The essay discusses both the pros and cons of animal testing while exploring emerging alternatives in modern science.
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