Cleaning Efficacy of Toothpastes With Varying Abrasiveness-An In Vitro Investigation on Bovine Dentin.

Objective: To determine how differences in abrasiveness (RDA) influence cleaning capabilities of toothpastes.

Methods: For this in vitro trial, 60 bovine dentin samples were prepared and divided into six groups (G1-G6; n = 10). Groups G1-G5 were arranged in order from low to high toothpaste abrasiveness (G1: RDA: 12, G2: RDA: 29, G3: RDA: 43, G4: RDA: 71, and G5: RDA: 143).

Transformer-based spatial-temporal detection of apoptotic cell death in live-cell imaging.

Intravital microscopy has revolutionized live-cell imaging by allowing the study of spatial-temporal cell dynamics in living animals. However, the complexity of the data generated by this technology has limited the development of effective computational tools to identify and quantify cell processes. Amongst them, apoptosis is a crucial form of regulated cell death involved in tissue homeostasis and host defense.

Masticatory Muscles Activation and TMJ Space During Asymmetrically Loaded Jaw Closing.

Masticatory muscle activation and temporomandibular joint (TMJ) load generated during asymmetrically loaded jaw closing are largely unknown. Two different strategies were developed to explain how the central nervous system (CNS) generates muscle activation patterns during motion: minimization of joint load (MJL) vs. minimization of muscle effort (MME).

Salivary Flow Rate During Toothbrushing.

Purpose: To determine the salivary flow rate and subsequent dilution of toothpaste and assess the pH of oral fluids during toothbrushing with toothpastes of various pHs.

Materials And Methods: The study was conducted as an in-vivo trial involving 30 healthy volunteers. The participants took part in a series of trials distributed over four appointments.

CANCOL, a Computer-Assisted Annotation Tool to Facilitate Colocalization and Tracking of Immune Cells in Intravital Microscopy.

Two-photon intravital microscopy (2P-IVM) has become a widely used technique to study cell-to-cell interactions in living organisms. Four-dimensional imaging data obtained via 2P-IVM are classically analyzed by performing automated cell tracking, a procedure that computes the trajectories followed by each cell. However, technical artifacts, such as brightness shifts, the presence of autofluorescent objects, and channel crosstalking, affect the specificity of imaging channels for the cells of interest, thus hampering cell detection.