Publications by authors named "A Puget"
Neuronal nerve processes in the tumor microenvironment were highlighted recently. However, the origin of intra-tumoral nerves remains poorly known, in part because of technical difficulties in tracing nerve fibers via conventional histological preparations. Here, we employ three-dimensional (3D) imaging of cleared tissues for a comprehensive analysis of sympathetic innervation in a murine model of pancreatic ductal adenocarcinoma (PDAC).
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- Gut dysbiosis is linked to both intestinal and extraintestinal cancers; however, the relationship between cancer development and changes in the microbiome is still unclear.
- The study found that cancer can cause damage to the ileal mucosa, leading to changes in gut permeability and a rise in Clostridium species, which are associated with dysbiosis.
- Interventions like β-adrenergic receptor blockers or antibiotics helped prevent the detrimental gut changes linked to tumors, suggesting stress ileopathy is an important condition in cancer that needs targeted treatment.
Early psychological care of the French victims of the Costa Concordia shipwreck.
Int Marit Health
March 2014
Most of the French passengers who survived the shipwreck of the cruise ship Costa Concordia were repatriatedfrom Italy to Marseille, one of the stopovers of the cruise. The shipwreck happened during the nightof 13th-14th January 2012 and entailed the forced evacuation of 4195 passengers and crewmembers.Thirty-two persons died and 2 others are still reported missing.
View Article and Find Full Text PDFBackground: Recent data about hepatitis A virus (HAV) seroprevalence in industrialized countries and the impact of travels to endemic areas are sparse or absent, particularly for children.
Objective: To determine the impact of travel to endemic areas on HAV seroprevalence and estimate the overall HAV seroprevalence in children in France. To identify risk factors for positive HAV serologic results.