Monocyte adherence to endothelial cells in vitro is increased by beta-VLDL.

The adherence of blood monocytes to the arterial endothelium is an early event in the development of atherosclerotic lesions. The possibility was investigated that alterations in the level and composition of plasma lipoproteins may contribute to this phenomenon. The adherence of human mononuclear cells to primary bovine aortic endothelial cells was measured in an in vitro monolayer collection assay.