[Moniside (isosorbide-5-mononitrate)--the effect on some changes in a hyperlipoproteinemia mode in rats].

The influence of the preparation moniside (isosorbide-5-mononitrate on some functional, lipid and enzymic changes in a model of hyperproteinemia of rats was investigated. Studies were carried out on 45 male rats, divided into 3 groups: I group-control, nontreated; II group--control treated with cholesterol diet; III group--experimental treated with cholesterol diet and monoside in a dose of 20 mg/kg of body weight orally 6 days a week. The experiment continued 3 months.

[Analysis of the autopsy data on 48 cases of infectious endocarditis in patients over 14].

Forty eight cases with infections endocarditis (IE) are analyzed--27 males and 21 females (75% at the age of 31-60). Only in 12.5% IE has developed on intact valvular apparatus.

[Acute myocardial infarct in embolizing abacterial thromboendocarditis (2 cases)].

Two patients are described, aged 60, with acute symptomless myocardial infarctions, diagnosed while still alive by electrocardiography, on the background of predominating neurological symptomatics, admitted as a manifestation of ischemic cerebral strokes, and in one of the patients--as embolization of peripheral artery, confirmed at operation. Multiple embolism and infarctions, with different duration, of brain and some other internal organs were established at necropsy, that originated from abacterial thromboendocarditis of aortic valve that developed in the absence of other diseases or data for the existence of disseminated intravasal coagulation. In the first case--extensive posterior-septal myocardial infarction was established and in the second--two not extensive infarctions, localized high anterior-septally and in the free anterior left ventricular wall.

[Familial idiopathic congestive cardiomyopathy in 2 brothers with a similar course].

The course of idiopathic congestive cardiomyopathy in two full brothers is described. The diagnosis was made on the base of the existing cardiomegaly, gallop rhythm and congestive cardiac insufficiency, in the absence of any connection with some of the well known causes for hypertrophy and dilation of the heart. It was confirmed at necropsy in one of the brothers.