[A simple test for the monitoring of plasma anti-XA activity of patients following subcutaneous administration of enoxaparin].

Since low molecular weight heparin is used for the prevention of thromboembolism, the coagulation laboratories are in need of a simple, reliable and practicable test for factor Xa inhibition in order to monitor the effect of low molecular heparin in plasma. Effects of subcutaneous administration of 20 mg or 40 mg enoxaparin were studied in blood samples drawn from 20 patients before and 1, 2, 3, 4, 6, 12 and 24 hours after injection. Thrombin time, aPTT, Heptest and the anti-Xa activity (amidolytic assay) were measured.

[Surgery of resectable liver metastases].

Criteria for the operability of liver-metastases are expectancies for complete cure, prolongation of life and improvement of life-quality. Results from our own department are reported.

[When is resection of liver metastases indicated?].

Indications for resection: radical removal of the primary tumor, extrahepatic metastases are not manifest, unilateral involvement of the liver. Because of the increasing safety also of wide resections (lethality 0-8%) and the good quality of life after resection the range of indications has been extended: bilateral operations, intra- and extrahepatic dilatations, metastases at the portal or venous hilus, palliative resections, lymphectomy. Primary tumors: colon and rectum, kidney, corpus uteri, sarcomas and carcinoids of the gastrointestinal tract, selected cases of all kinds.

[Studies in the diagnosis of breast disease (author's transl)].

The relative diagnostic accuracy of clinical examination, mammography, thermography and ultrasound was investigated in a comparative study. Mammography proved to be the most accurate diagnostic method, followed by clinical examination, thermography and ultrasound. Whereas in cases of advanced cancer (T2 to T4 tumour diameter greater than 2 cm) the correct diagnosis was made most reliably by clinical examination, mammography was superior to all other procedures in T1 tumours and in impalpable tumours.