Publications by authors named "A Pozzuoli"
Background: Diabetic foot is one of the major complications of diabetes, affecting 15% of patients with diabetes. This study aims to evaluate and compare the clinical and radiographic outcomes of patients with diabetes affected by forefoot plantar preulcerative or ulcerative lesions who have undergone minimally invasive distal metatarsal diaphyseal osteotomy (MIS-DMDO) to assess its efficacy in the prevention and treatment of chronic plantar diabetic foot ulcers (CPDFUs).
Methods: The study included 60 patients, 38 with preulcers and 22 with ulcers, with at least 2 years of clinical and radiologic follow-up.
Musculoskeletal diseases (MSDs) comprise a plethora of different disorders (more than 150 conditions) affecting the locomotor system [...
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- Plantar adipose tissue, located in different regions of the foot, adapts its structure and mechanical properties to absorb impact and support body weight.
- The study involved experiments on human tissue samples that measured the elastic properties and non-linear behavior of plantar adipose tissue in various foot regions.
- Results demonstrated significant differences in elastic moduli across regions, leading to the development of a visco-hyperelastic model that may be useful for future computational models of foot biomechanics.
Article Synopsis
- Chondrosarcomas show varied behavior, making it difficult to predict outcomes based solely on histology, prompting interest in genetic markers like IDH mutations for better prognosis.
- The study aimed to determine how common IDH mutations are in chondrosarcoma patients and if certain mutations correlate with survival outcomes like overall survival and recurrence-free survival.
- Out of 74 treated patients, 41 were included in the study, where DNA was analyzed for IDH mutations, revealing that 56% of eligible patients had sufficient DNA for analysis.