New beam delivery system design for industrial electron accelerator at Nuclear Science and Technology Research Institute, Iran.

The output beams generated by industrial electron accelerators should be swept over the product. It is necessary to determine the exact scan length in order to ensure that an efficient dose reaches the product and to avoid the loss of the beam in contact with the sides of the product. Another challenge associated with scanning beams is the non-uniformity of the dose across the entire product during irradiation.

Adhesion of monocytes and endothelial cells isolated from the human aorta suppresses by miRNA-PEI particles.

Background: Knowledge of stenosis in coronary arteries requires an understanding of the cellular and molecular processes that occur throughout the leukocyte rolling process. In this study, the roles of miR-125a-5p and miR-495-3p were investigated on the adhesion of endothelial cells (ECs) isolated from the human aorta.

Methods: Human primary endothelial cells were obtained from the aorta of people who had died of brain death.

Effect of a Peptide Construct on Differentiated Macrophage MMP-2 and MMP-9 Levels of Varicose Patients.

Background: The Matrix Metalloproteinase (MMPs) secreted from macrophages can affect the extracellular matrix remodeling process and improve varicose veins.

Aim: The aim of this study was to investigate the MMP-2 and MMP-9 gene expression and activity levels in the differentiated macrophages M2 of subjects with varicose veins, and to evaluate a peptide construct on their catalytic functions.

Methods: The macrophages were differentiated from the monocytes using M-CSF.

Isolation of intimal endothelial cells from the human thoracic aorta: Study protocol.

Vessel endothelial cells are extensively applied to study the mechanism of atherosclerosis. Some cellular sources including human umbilical artery endothelial cells (HUAECs) and human umbilical vein endothelial cells (HUVECs) are mostly applied in the experimental studies. We described a method for isolating the human endothelial cells from the human thoracic aorta.

The effects of oxidative stress on the development of atherosclerosis.

Atherosclerosis is a cardiovascular disease (CVD) known widely world wide. Several hypothesizes are suggested to be involved in the narrowing of arteries during process of atherogenesis. The oxidative modification hypothesis is related to oxidative and anti-oxidative imbalance and is the most investigated.