Publications by authors named "A Poudyal"
The disadvantaged populations eGFR (estimated glomerular filtration rate) epidemiology (DEGREE) study was designed to gain insight into the burden of chronic kidney disease (CKD) of undetermined cause (CKDu) using standard protocols to estimate the general-population prevalence of low eGFR internationally. Therefore, we estimated the age-standardized prevalence of eGFR under 60 ml/min per 1.73m in adults aged 18-60, excluding participants with commonly known causes of CKD; an ACR (albumin/creatinine ratio) over 300 mg/g or equivalent, or self-reported or measured (HT) hypertension or (DM) diabetes mellitus, stratified by sex and location.
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- The study evaluated adherence to healthcare waste management (HCWM) practices and knowledge among handlers in 10 district hospitals of Madhesh Province using a mixed-method approach, including surveys and interviews.
- Findings showed that among 60 participants, most were female with a median age of 35, a significant portion was illiterate, and the average adherence to HCWM practices was 74.88%, indicating room for improvement in waste management education and practices.
Article Synopsis
- The DEGREE study explored the impact of chronic kidney disease of undetermined cause (CKDu) globally by analyzing the prevalence of low estimated glomerular filtration rate (eGFR) in adults aged 18-60, focusing on participants without known CKD causes.
- The study included data from 60,964 participants across 43 areas in 14 countries collected from 2007 to 2023, revealing the highest CKDu prevalence in rural areas of Uddanam, India, and Northwest Nicaragua (14%).
- The findings indicate that CKDu is notably prevalent in specific regions, especially within Central America and South Asia, prompting the need for global monitoring while acknowledging the potential existence of unidentified disease clusters elsewhere.
Article Synopsis
- The study aims to estimate the prevalence of Coronary Artery Disease (CAD) and its risk factors in Nepal, highlighting it as a significant health issue.
- A survey with 12,557 participants aged 20 and older revealed a prevalence of 0.5% for definite CAD, 2.1% for possible CAD, and 0.3% for probable CAD, with higher rates in certain demographics.
- The findings indicate a notable burden of CAD in Nepal, emphasizing the need for targeted interventions at both individual and population levels to address the disease and its risk factors.
Article Synopsis
- - The COVID-19 pandemic, first identified in Wuhan, China in December 2019, prompted a study in Nepal to analyze morbidity and mortality linked to the virus across different demographics.
- - The analysis highlighted that case rates were higher in males, especially those aged 31-40 years, while the case fatality rate increased with age, particularly in older males compared to females.
- - Findings indicated that COVID-19 case rates were highest in the Bagmati province, whereas the highest case fatality rates occurred in poorer districts, especially in hilly and mountainous areas of provinces like Province 1, Gandaki, and Karnali.