Benzodiazepine use for anxiety disorders is associated with increased long-term risk of mood and substance use disorders: A large-scale retrospective cohort study.

Background: Benzodiazepines (BZDs) are widely prescribed for anxiety disorders. However, the long-term implications on mental health remain uncertain, especially the potential association between chronic BZD use and subsequent diagnosis of mood and substance use disorders (SUDs).

Method: We conducted a 5-year retrospective cohort study by analyzing the TriNetX database, a real-time electronic medical record network.

A Unique Delusion with Depression in Early Stage of Neurocognitive Disorder Due to Vascular Disease: Considerations for Clinicians.

As global aging becomes more prominent, neurocognitive disorders (NCD) incidence has increased. Patients with NCD usually have an impairment in one or more cognitive domains, such as attention, planning, inhibition, learning, memory, language, visual perception, and spatial or social skills. Studies indicate that 50-80% of these adults will develop neuropsychiatric symptoms (NPS), such as apathy, depression, anxiety, disinhibition, delusions, hallucinations, and aberrant motor behavior.

Decommissioning of a Medical Cyclotron Vault: The Case Study of the National Cancer Institute of Milano.

In the widespread use of medical cyclotrons for isotope production, radiological and economic consequences related to the decommissioning of particle accelerators are often neglected. However, decommissioning regulation and its related procedures always demand efforts and costs that can unexpectedly impact on budgets. The magnitude of this impact depends strongly on the residual radioactivity of the accelerator and of the vault, and more specifically on the kind and activity concentration of residual radionuclides.

Prediction of Microstructure for AISI316L Steel from Numerical Simulation of Laser Powder Bed Fusion.

Abstract: Laser powder bed fusion (L-PBF) success in the industrial scenario strongly depends on the ability to manufacture components without defects and with high building rates, but also on the ability to effectively control the microstructure to gain the required properties in the final component. In this regard, the recently developed numerical simulation software of L-PBF technologies can represent an effective tool, since many of them provide solidification data (i.e.