Publications by authors named "A Pilling"
. We describe a patient with normal tension glaucoma (NTG) of several years whose management was complicated by the presence of a giant internal carotid-ophthalmic artery aneurysm. .
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- The study looked at how often men with advanced prostate cancer get tested with a special method called next-generation sequencing (NGS) to find helpful information about their disease.
- They analyzed data from 1,597 patients and found that only 9% had more than one NGS test, often discovering new useful information on the second test.
- The results suggest that doing these tests more than once could help doctors make better treatment choices for men with advanced prostate cancer.
Importance: Black men have higher incidence and mortality from prostate cancer. Whether precision oncology disparities affect Black men with metastatic castration-resistant prostate cancer (mCRPC) is unknown.
Objective: To compare precision medicine data and outcomes between Black and White men with mCRPC.
Purpose: African American individuals are disproportionately affected by lung cancer in terms of incidence and mortality. In oncogene-driven non-small-cell lung cancer (NSCLC), emerging evidence indicates that underlying molecular heterogeneity, which can be affected by ancestry, contributes to variable drug sensitivity and therapeutic responses. The purpose of this study was to evaluate race-associated differences in reported treatment decisions, therapeutic outcomes, and molecular features in and -mutant NSCLC.
View Article and Find Full Text PDFBackground: Inactivating alterations in SPOP frequently occur in prostate cancer and promote increased dependency on androgen receptor (AR)-mediated oncogenic signaling. The presence of SPOP mutation (SPOP-mutant [SPOP-mut]) may therefore impact therapeutic outcomes with AR-directed therapies and docetaxel in metastatic castration-resistant (mCRPC).
Methods: This was a retrospective study of mCRPC patients treated at an urban academic hospital (n = 103).