Publications by authors named "A Pilleri"
Article Synopsis
- * Differences in how drugs are metabolized by sex highlight the need for sex-specific medical approaches, yet awareness of this issue is still limited.
- * The paper focuses on evaluating therapeutic strategies for managing common diseases affecting women, emphasizing the importance of individualized treatment guidelines based on gender.
Article Synopsis
- Heart failure with preserved ejection fraction (HFpEF) is becoming more common, especially in older adults and people with health issues like obesity and high blood pressure.
- New treatments have shown to help patients live better and stay out of the hospital longer.
- Understanding each patient's specific needs is important for better care, but many people with HFpEF are still not diagnosed or treated properly.
Article Synopsis
- - Gender significantly influences cardiovascular risk factors and affects prevention, clinical pathways, diagnosis, and treatment, highlighting the need for a more inclusive approach in healthcare.
- - Despite its importance, sex and gender differences in cardiovascular care are often overlooked, leading to disparities in patient outcomes and access to quality care.
- - The paper emphasizes the necessity of increasing female representation in clinical trials and leadership roles, advocating for tailored treatment strategies that consider gender influences on cardiovascular diseases.
Anderson-Fabry disease (AFD) is a lysosome storage disorder resulting from an X-linked inheritance of a mutation in the galactosidase A (GLA) gene encoding for the enzyme alpha-galactosidase A (α-GAL A). This mutation results in a deficiency or absence of α-GAL A activity, with a progressive intracellular deposition of glycosphingolipids leading to organ dysfunction and failure. Cardiac damage starts early in life, often occurring sub-clinically before overt cardiac symptoms.
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- Recent advancements in percutaneous treatments for heart conditions have led to increased radiation exposure for interventional cardiologists, raising concerns about associated health risks like cancer and neurodegenerative disorders.
- *The general lack of awareness among operators about their radiation exposure risk, coupled with ineffective preventive measures, highlights a significant safety issue.
- *The ANMCO position paper aims to raise awareness among operators and propose strategies to reduce radiation doses and the associated health risks.*