[Sporadic case of leptospirosis].

The flood disaster involves the danger of development of dangerous epidemic and episodic events on leptospirotic endemic area in the nearest spring and summer. The authors present a case of severe hemolytic leptospirosis as a results of gastrointestinal tract infection of 3 strains of leptospira. Polymorphism leptospirotic symptoms were discussed.

[Plasma pancreatic glucagon during glucose tolerance test in workers exposed to vibration and noise].

Pancreatic glucagon plasma concentration (IR-G) were measured during oral glucose tolerance test (GTT) in workers exposed to whole body vibration and noise. In workers with abnormal GTT higher IR-G concentrations were found in comparison with the control group. Langerhans islet alfa cells stimulation may be responsible for a higher frequency of elevated glycemia during GTT in workers exposed to whole body vibration and noise.

[Secretion of insulin and peptide C in workers exposed to whole body vibration and noise].

Insulin and C-peptide concentrations were studied in serum (by means of radioimmunoassay) after an oral glucose tolerance test in 62 workers occupationally exposed to whole body vibration and noise, and in 30 non-exposed workers of the control group. In the exposed group more frequent occurrence of higher glucose and insulin concentrations, with normal C-peptide concentrations, were found. The observed non-effective hyperinsulinaemia is likely caused by an impaired insulin degradation in the liver and/or an increased production of proinsulin which is assayed simultaneously by IR-I method.

[Low frequency vibration and testosterone levels in blood serum and excretion of 17-ketosteroid in urine in exposed workers].

Serum testosterone concentrations and excretion of 17-Ketosteroid in urine were determined in 32 caterpillar vehicle drivers exposed to low frequency vibration of the whole body and to noise. Testosterone concentrations were assessed by the RIA method in fasting after 3 hrs of work. 17-Ketosteroid excretion was measured in the 8-hr collection of night urine and in urine collected during the day's work.

[Glucose tolerance test and insulinemia in workers occupationally exposed to vibration and noise].

Oral glucose test and serum insulin determination was performed in 192 workers of a large metallurgical factory. The subjects were divided into four groups: 1. exposed to isolated noise, 2.