Publications by authors named "A Piccardo"

Recent research has proposed using positron emission tomography/computed tomography (PET/CT) along with the administration of prostate-specific membrane antigen (PSMA)-targeting radiopharmaceuticals to identify breast cancer (BC) lesions. An extensive literature review to investigate the possible diagnostic utility of PET/CT with PSMA-targeting radiopharmaceuticals in BC patients was performed. The research comprised different clinical scenarios, including both newly diagnosed BC patients and those who had experienced disease relapse.

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  • Cardiac neuroendocrine tumour metastases (CNTM) are uncommon, but advances in SSTR-PET/CT imaging may help detect them more frequently, prompting this systematic review and meta-analysis.
  • A total of ten studies with 163 patients showed that SSTR-PET/CT detects CNTM earlier than other imaging methods, with a pooled prevalence of 1.5% among neuroendocrine neoplasm (NEN) patients undergoing the procedure.
  • The findings suggest that SSTR-PET/CT improves early detection of CNTM but indicate a need for more thorough studies to assess its effects on patient outcomes and treatment decisions in NEN cases.
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  • PET imaging with [F]F-DOPA shows promise for assessing pediatric brain gliomas, but manual extraction of data is slow and inconsistent.
  • A new semi-automated Python framework was developed to streamline the processing of PET images and improve efficiency and accuracy in calculating clinical scores.
  • The study found that this new method significantly improved reproducibility in extracting important tumor metrics and reduced the variability associated with human input.
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Introduction: The article aims to outline the features of the efforts for smallpox eradication within the pre-unitary context of the Kingdom of Sardinia, characterized by a long tradition in medical-health prevention. This tradition is partly inherited from the health magistracies of the Italian states during the ancient regime and partly adopted from policies initially outlined by Napoleon and later by other European states. In addition to prevention activities, authorities also engage in a vigorous information and awareness campaign aimed at eliminating common prejudices and doubts about vaccination among the population.

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  • A study evaluated the effectiveness of a diagnostic strategy combining [F]Fluorocholine PET/CT with 4D-CT for patients with primary hyperparathyroidism (pHPT) undergoing surgery.
  • The results showed that PET/CT was significantly more accurate than 4D-CT, with high sensitivity and specificity rates (83% and 97%, respectively), whereas 4D-CT had lower rates (53% sensitivity).
  • When PET/CT results were inconclusive, using the two imaging methods together improved diagnostic accuracy, making it a recommended personalized imaging approach for pHPT patients.
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