Publications by authors named "A Petoukhova"
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Cosmetic outcome in patients with early stage breast cancer after accelerated partial breast irradiation using intraoperative or external beam radiotherapy.
Jetske L B Gunster Daphne H M Jacobs Mirjam E Mast Antoinette Verbeek-de Kanter Ursula J Fisscher Anna L Petoukhova
Clin Transl Radiat Oncol
November 2024
Article Synopsis
- The study evaluated cosmetic outcomes in early stage breast cancer patients using either intraoperative electron radiotherapy (IOERT) or photon external beam radiotherapy (EB-APBI) after breast-conserving surgery over a 5-year follow-up period.
- A total of 405 patients (241 treated with IOERT and 164 with EB-APBI) showed that both treatments resulted in high satisfaction rates among patients and physicians, with no significant differences in cosmetic outcomes over time.
- The conclusion indicates that both IOERT and EB-APBI provide comparable and satisfactory cosmetic results for early stage breast cancer patients, with similar ratings from both subjective and objective assessments.
Article Synopsis
- This study compares Monte Carlo (MC) and Collapsed Cone (CC) dose algorithms in RayStation 12A for 6 MV and 6 MV flattening filter-free (FFF) photon beams used in radiotherapy plans involving small and highly modulated fields.
- It assesses how these algorithms perform in output dose measurements, examining their accuracy across various configurations such as rectangular and complex clinical plans.
- Results indicate that while both algorithms show dependency on collimator angles in narrow fields, MC may perform better in highly modulated scenarios, but is less reliable with inhomogeneous ArcCHECK images, suggesting the need for homogeneous phantom setups for verification.
Dosimetric Analyses of the Three Radiation Techniques Used in the EORTC 22922/10925 IM-MS Breast Cancer Trial.
Clin Oncol (R Coll Radiol)
November 2024
Article Synopsis
- The study compares dosimetry of three radiation therapy techniques for targeting internal mammary and supraclavicular nodes in breast cancer treatment, as part of the EORTC 22922/10925 trial.
- A retrospective analysis of ten randomly selected left-sided breast cases was conducted, assessing plans according to trial protocols, where doses to planning target volumes and organs at risk were measured.
- Results showed that while all techniques adequately dosed the breast and supraclavicular regions, the individualized plan had lower internal mammary coverage, but reduced heart exposure compared to standard techniques, suggesting benefits in treatment planning for breast cancer outcomes.
Article Synopsis
- The study focuses on validating the updated Lung-molGPA prognostic model to predict survival in patients with brain metastases from non-small cell lung cancer after treatment with stereotactic radiotherapy.
- A total of 241 patients were analyzed using various prognostic factors to assess their survival rates through statistical methods like Kaplan-Meier analysis and Cox proportional hazard model.
- Results showed that while the Lung-molGPA accurately predicted survival in most patient groups, it slightly overestimated survival for patients in the most favorable prognostic category.