THE FIRST REPORT OF LAPAROSCOPIC RADICAL CYSTECTOMY IN GEORGIA.

Bladder cancer is the ninth most commonly diagnosed malignant tumor worldwide. Radical cystectomy is the standard surgical treatment for non-metastatic, muscle-invasive bladder cancer and a recommended treatment of choice in a subset of highest-risk patients with non-muscle invasive disease. Recently, laparoscopic radical cystectomy has become an attractive alternative to an open counterpart and many centers worldwide have reported their early experiences with the technique.

Metastasis of renal cell carcinoma to contralateral adrenal gland: case report and review of the literature.

Isolated metastasis of renal cell carcinoma (RCC) to the contralateral adrenal gland is a rare complication occurring in 2.5% of cases. The optimal diagnosis and treatment of this condition is not well defined.

The value of nephron-sparing surgery for the treatment of renal cell carcinoma 4 to 7 cm in size.

Nephron-sparing surgery (NSS) is a treatment of choice for renal cell carcinoma (RCC) less than 4 cm. in size. However its efficacy in the treatment of RCC from 4cm to 7 cm is not well defined and is still controversial.

Treatment of renal cell carcinoma in pregnancy: simultaneous nephron-sparing surgery and Caesarian section (case report).

We present a case of a 33-year-old pregnant woman with renal cell carcinoma diagnosed at 24 weeks of gestational age. Simultaneous nephron sparing surgery (NSS) and Caesarean section (CS) was performed at 33 weeks of gestation. The successful cases of radical nephrectomy performed in pregnancy have been reported earlier however, we believe this is the first case of NSS and CS performed simultaneously.

Immunoreactivity of p27(Kip1), cyclin D3, and Ki67 in conventional renal cell carcinoma.

The goal of the study was to evaluate expression of the cell-cycle regulatory proteins (p27(Kip1) and cyclin D3) and proliferation marker Ki67 in normal human kidneys and renal cell carcinoma (RCC) tissues. Intensity of the markers' expression was prospectively studied and compared between normal and RCC tissue samples. Association was analyzed with cancer clinical parameters.