Publications by authors named "A Persichetti"
Parcellations of resting-state functional magnetic resonance imaging (rs-fMRI) data are widely used to create topographical maps of functional networks in the human brain. While such network maps are highly useful for studying brain organization and function, they usually require large sample sizes to make them, thus creating practical limitations for researchers that would like to carry out parcellations on data collected in their labs. Furthermore, it can be difficult to quantitatively evaluate the results of a parcellation since networks are usually identified using a clustering algorithm, like principal components analysis, on the results of a single group-averaged connectivity map.
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- * They found that ASD individuals displayed atypical functional network patterns, specifically in the stability of connectivity across brain regions, weaker differentiation of specific brain areas, and unusual integration of subcortical structures with the neocortex.
- * The findings suggest that individuals with ASD have distinct brain connectivity patterns that differ from typically developing individuals, highlighting how their brain networks may function differently.
Purpose: High resolution fMRI is a rapidly growing research field focused on capturing functional signal changes across cortical layers. However, the data acquisition is limited by low spatial frequency EPI artifacts; termed here as Fuzzy Ripples. These artifacts limit the practical applicability of acquisition protocols with higher spatial resolution, faster acquisition speed, and they challenge imaging in lower brain areas.
View Article and Find Full Text PDFItalian Guidelines for the Management of Sporadic Primary Hyperparathyroidism.
Endocr Metab Immune Disord Drug Targets
June 2024
Article Synopsis
- The guideline is designed to help healthcare professionals manage sporadic primary hyperparathyroidism (PHPT) in adults, excluding cases during pregnancy.
- Developed through a systematic review process, the guideline focuses on identifying critical outcomes that impact treatment decisions, emphasizing pharmacological and surgical options.
- Key recommendations include recommending parathyroidectomy for symptomatic patients or those with specific criteria, while also providing guidance for monitoring other related health issues.
Aim: This guideline (GL) is aimed at providing a clinical practice reference for the management of adult patients with overweight or obesity associated with metabolic complications who are resistant to lifestyle modification.
Methods: Surgeons, endocrinologists, gastroenterologists, psychologists, pharmacologists, a general practitioner, a nutritionist, a nurse and a patients' representative acted as multi-disciplinary panel. This GL has been developed following the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach.