[Use of antidepressants in unipolar depression in the elderly].

Objective: To study the ageing-related pharmacological modifications about major depressive episodes in the elderly and their impact on the efficiency and tolerability of antidepressants.

Methods: Research through Pubmed and the Cochrane Database of Systematic Reviews, using the following keywords "antidepressant" ; "treatment"; "late life depression"; "elderly"; up until July 2021.

Results: Antidepressants were found to be more efficient than a placebo in the elderly's response to and remission from major depressive episodes.