Abf1 negatively regulates the expression of and affects adhesion in .

. Adherence is a major virulence trait in that, in many strains, depends on the (epithelial adhesin) genes, which confer the ability to adhere to epithelial and endothelial cells of the host. The genes are generally found at subtelomeric regions, which makes them subject to subtelomeric silencing.

From Web to RheumaLpack: Creating a Linguistic Corpus for Exploitation and Knowledge Discovery in Rheumatology.

This study introduces RheumaLinguisticpack (RheumaLpack), the first specialised linguistic web corpus designed for the field of musculoskeletal disorders. By combining web mining (i.e.

Microevolution of Candida glabrata (Nakaseomyces glabrata) during an infection.

Candida glabrata (Nakaseomyces glabrata) is an emergent and opportunistic fungal pathogen that colonizes and persists in different niches within its human host. In this work, we studied five clinical isolates from one patient (P7), that have a clonal origin, and all of which come from blood cultures except one, P7-3, obtained from a urine culture. We found phenotypic variation such as sensitivity to high temperature, oxidative stress, susceptibility to two classes of antifungal agents, and cell wall porosity.

Characterization of a New Immunosuppressive and Antimicrobial Peptide, DRS-DA2, Isolated from the Mexican Frog, .

Inflammatory and antimicrobial diseases constitute a major burden for society, and fighting them is a WHO strategic priority. Most of the treatments available to fight inflammatory diseases are anti-inflammatory drugs, such as corticosteroids or immunomodulators that lack cellular specificity and lead to numerous side effects. In addition to suppressing undesired inflammation and reducing disease progression, these drugs lessen the immune system protective functions.

Bioclimatic Characterisation of Specific Native Californian Pinales and Their Future Suitability under Climate Change.

Rising temperatures and changes in precipitation patterns under climate change scenarios are accelerating the depletion of soil moisture and increasing the risk of drought, disrupting the conditions that many plant species need to survive. This study aims to establish the bioclimatic characterisation, both qualitative and quantitative, of ten native Californian Pinales for the period 1980-2019, and to determine their habitat suitability by 2050. To achieve this, an exhaustive search of the Gbif database for records of ten conifer taxa was carried out.