[Experiences with the treatment of chronic hepatitis C and prognostic factors for its efficacy in clinical practice].

Objective: The study aimed at evaluating antiviral therapy and the impact of selected factors on its efficacy in patients with chronic hepatitis C treated at the Department of Infectology and Travel Medicine in Kosice, Slovakia, between 2003 and 2007.

Material And Methods: A retrospective analysis of a group of 213 patients treated for chronic hepatitis C and of prognostic factors for treatment efficacy in a subgroup of 159 patients who completed therapy with pegylated interferon alpha and ribavirin.

Results: From the entire group, 193 patients were treated with a combination of pegylated interferon and ribavirin, 5 received pegylated interferon monotherapy and in 15 cases, conventional interferon was used.

[Haematologic adverse effects of treatment of chronic viral hepatitis B and C].

Objective: To determine the incidence and severity of adverse effects of treatment in patients with chronic hepatitis B and C (CHB and CHC).

Material And Methods: A group of 104 patients with CHC and 74 CHB patients treated in 1994-2005 was evaluated. The patients were divided according to their treatment patterns and sex.

[Löffler's endocarditis].

The authors describe Loeffler's endocarditis and the treatment of this clinical entity. Among diagnostic methods which drew attention to a cardiac affection associated with eosinophilia, non-invasive examination methods were of decisive importance. They comprised conventional electrocardiographic examination, X-ray of the chest and two-dimensional echocardiography.