Short-time recovery skeletal muscle from dexamethasone-induced atrophy and weakness in old female rats.

Background: Several pathological conditions (atrophy, dystrophy, spasticity, inflammation) can change muscle biomechanical parameters. Our previous works have shown that dexamethasone treatment changes skeletal muscle tone, stiffness, elasticity. Exercise training may oppose the side effects observed during dexamethasone treatment.

Better Economy on Indoor Track Compared to Treadmill Running With 1% Inclination.

: The purpose of this study was to investigate the differences in metabolic responses between the track and the treadmill (1% inclination) running. The latter is recommended for use in laboratory settings to mimic outdoor running. : Seventeen male endurance athletes (mean 25.

Changes in Body Composition of Old Rats at Different Time Points After Dexamethasone Administration.

Background: Aging leads to changes in skeletal muscle quantity and quality and is accompanied with increase in body mass and fat mass, whereas fat-free mass either decreases or remains unchanged. The body composition of rodents has been an important factor for clinical trials in the laboratory. Glucocorticoids such as dexamethasone are widely used in clinical medicine, but may induce myopathy, characterized by muscle weakness, atrophy, and fatigue.

Glucocorticoid-Induced Changes in Rat Skeletal Muscle Biomechanical and Viscoelastic Properties: Aspects of Aging.

Objectives: The purpose of this study was to estimate the state of tension (tone) and the biomechanical and viscoelastic properties of skeletal muscle in aging rats during the administration of different doses of dexamethasone and to find the relationships among the state of muscle atrophy, muscle strength, and the abovementioned muscle properties.

Methods: Muscle state of tension, biomechanical (elasticity, dynamic stiffness) and viscoelastic (mechanical stress relaxation time, Deborah number) properties (using MyotonPRO, Myoton Ltd, Tallinn, Estonia), lean body mass (BM), and hind limb grip strength were measured before and after the administration of a 10-day treatment with dexamethasone 100 μg/100 g BM (young and old group) and 50 μg/100 g BM (old group).

Results: Muscle elasticity (logarithmic decrement) was lower in old animals (1.

Lower Leg Length is Associated with Running Economy in High Level Caucasian Distance Runners.

The aim of the present study was to investigate lower limb anthropometric and composition variables related to running economy (RE) and running performance in a homogeneous group of high level European distance runners. RE at the speeds of 14, 16 and 18 km·h (189 ± 12; 188 ± 11; 187 ± 11 O ml·kg·km) and maximal oxygen uptake (VO) (67.3 ± 2.