Publications by authors named "A Pavy-Le Traon"
Background: Spinocerebellar ataxia 27B is the most common genetic late onset cerebellar ataxia (LOCA). However, it commonly overlaps with other genetic LOCA as with the cerebellar form of multiple system atrophy (MSA-C).
Objectives: To pinpoint which clinical signs and symptoms best discriminate between FGF14 + from FGF14 - patients at symptoms' onset.
Space analog research has increased over the last few years with new analogs appearing every year. Research in this field is very important for future real mission planning, selection and training of astronauts. Analog environments offer specific characteristics that resemble to some extent the environment of a real space mission.
View Article and Find Full Text PDFAutonomic nervous system education in Europe: EAN/EFAS/INUS survey on curricula and skills in autonomic medicine of European neurology residents and consultants.
Eur J Neurol
December 2024
Article Synopsis
- The study evaluates the state of education and training in autonomic nervous system (ANS) disorders among European neurology residents and consultants, especially after disruptions caused by the COVID-19 pandemic.
- The research employed a 23-item online questionnaire distributed to neurology professionals, assessing demographics, training opportunities, and preferences for learning about ANS disorders.
- Results indicated a strong desire among 285 respondents for improved education in ANS skills, with notable differences based on gender, age, and region, highlighting the need for integrating autonomic medicine into residency curricula.
Article Synopsis
- The review outlines neuroprotection trials for multiple system atrophy (MSA), a serious neurodegenerative disease, and discusses important factors for conducting successful clinical trials, such as diagnosis and study design.
- Over 30 compounds have been evaluated in MSA trials, but only two have been successful in meeting their primary endpoint, indicating a need for better understanding of the disease.
- Current trials focus on targeting α-synuclein, a key feature of MSA, and emphasize the necessity of improving disease models, clinical measurement tools, and biomarker research to enhance future trial outcomes.
Purpose: To understand the influence of the coronavirus disease 2019 (COVID-19) pandemic on clinical autonomic education and research in Europe.
Methods: We invited 84 European autonomic centers to complete an online survey, recorded the pre-pandemic-to-pandemic percentage of junior participants in the annual congresses of the European Federation of Autonomic Societies (EFAS) and European Academy of Neurology (EAN) and the pre-pandemic-to-pandemic number of PubMed publications on neurological disorders.
Results: Forty-six centers answered the survey (55%).