Objective: To holistically evaluate the extent of implementation of dietary guidelines in schools and present various monitoring systems.
Design: The study comprises three methods: (i) a cross-sectional survey (process evaluation); (ii) an indicator-based evaluation (menu quality); and (iii) a 5 d weighed food record of school lunches (output evaluation).
Setting: Slovenian primary schools.
Proc Natl Acad Sci U S A
October 1987
Plasmodium falciparum-infected erythrocytes bind to venular endothelial cells by means of electron-dense deformations (knobs) on the parasitized erythrocyte surface. The primary structure of a parasite-derived histidine-rich protein associated with the knob structure was deduced from cDNA sequence analysis. The 634 amino acid sequence is rich in lysine and histidine and contains three distinct, tandemly repeated domains.
View Article and Find Full Text PDFBinding of antibodies to effector cells by way of receptors to their constant regions (Fc receptors) is central to the pathway that leads to clearance of antigens by the immune system. The structure and function of this important class of receptors on immune cells is addressed through the molecular characterization of Fc receptors (FcR) specific for the murine immunoglobulin G isotype. Structural diversity is encoded by two genes that by alternative splicing result in expression of molecules with highly conserved extracellular domains and different transmembrane and intracytoplasmic domains.
View Article and Find Full Text PDFThe nucleotide sequence of a complete genomic clone for the histidine-rich protein of Plasmodium lophurae has been determined. The deduced amino acid sequence of the mature protein shows numerous tandemly repeated units preceded by a signal and a pro peptide. The gene is interrupted by an intron with a separate exon coding for the signal peptide.
View Article and Find Full Text PDFWe have previously identified a number of cloned poly(A)+ RNA sequences in a cDNA library, each of whose expression is markedly altered in a dimethylhydrazine-induced mouse colon tumor as compared to the normal colon. Transcripts which hybridize to one of the cloned cDNAs, pMCT-1, have now been shown to be elevated in expression in three mouse leukemia cell lines as well, and induction of differentiation in one of these lines (DS-19) is associated with a substantial decrease in expression of these transcripts. By hybridization and sequence analysis, pMCT-1 has been found to contain a region homologous to a long terminal repeat of an intracisternal A particle sequence.
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