Publications by authors named "A Pauwels"

Article Synopsis
  • This study systematically reviewed and analyzed data on motor progression in Parkinson's disease (PD), emphasizing that current tools for assessing treatment effects are heavily influenced by dopaminergic therapies.
  • It found that untreated PD patients showed a significantly higher motor progression rate of 4.5% per year compared to only 1.6% for those receiving dopaminergic drugs, indicating the importance of considering treatment status in studies.
  • The research suggests that long-term measurements of motor progression can still be effective even after starting dopaminergic medications, but calls for careful study designs to reduce confounding factors associated with symptom treatment.
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Article Synopsis
  • Real-time symptom reporting during reflux monitoring is important for evaluating esophageal symptoms, but the psychological and physiological factors involved are not well understood.
  • A study was conducted with adult patients using questionnaires and pH-impedance monitoring to analyze how these factors influence symptom reporting.
  • Results showed that psychological factors like anxiety and physiological factors such as reflux episodes affect symptom frequency, but machine learning models struggled to accurately classify symptom associations, indicating complexity in understanding reflux symptoms.
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Objective: Orthopaedic surgery is an effective intervention for treating the symptoms of degenerative joint disease or osteoarthritis (OA). Frequent wound dressing changes, unless clinically indicated, can disrupt the healing process and increase the occurrence of incision site contamination. Protection from contamination is critical for surgical incisions and, therefore, undisturbed wound healing (UWH) in surgical wound management is vital.

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Osteoarthritis (OA) poses a growing challenge for the aging population, especially in the hip and knee joints, contributing significantly to disability and societal costs. Exploring the integration of wearable technology, this study addresses the limitations of traditional rehabilitation assessments in capturing real-world experiences and dynamic variations. Specifically, it focuses on continuously monitoring physical activity in hip and knee OA patients using automated unsupervised evaluations within the rehabilitation process.

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Background: The adverse effect of air pollution on mortality is well documented worldwide but the identification of more vulnerable populations at higher risk of death is still limited. The aim of this study was to evaluate the association between natural mortality (overall and cause-specific) and short-term exposure to five air pollutants (PM, PM, NO, O and black carbon) and identify potential vulnerable populations in Belgium.

Methods: We used a time-stratified case-crossover design with conditional logistic regressions to assess the relationship between mortality and air pollution in the nine largest Belgian agglomerations.

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