Publications by authors named "A Pasciucco"
PRES is a neuro-clinical and radiological syndrome that can result as a consequence of several different conditions including hypertension, fluid overload, and immunosuppressive treatment. Herein, we report two children who received kidney and combined liver-kidney transplantation as treatment for renal hypodysplasia associated with bilateral vesico-ureteral reflux and methylmalonic acidemia, respectively. Early after surgery (seven and 10 days), both patients presented with hypertension and seizures.
View Article and Find Full Text PDFThe aim of this study was to investigate the effectiveness of a synthetic polyethy lenglycol (PEG) sealant to prevent lymphocele formation after kidney transplantation. The examined group consisted of 719 recipients including 294 female and 425 male who were immunosuppressed with a calcineurin inhibitor, plus basiliximab since 1999, and with mycophenolate mofetil in addition since 2000. We retrospectively analyzed the incidence of lymphoceles among 545 recipients operated between November 1999 and November 2007 (group I), 93 recipients at standard risk for lymphocele transplanted between December 2007 and December 2009 (group II) in whom we performed only routine ligation of the lymphatic vessels during preparation of the graft, and 31 patients also transplanted between December 2007 and December 2009 who were at higher risk for lymphocele (group III) and underwent an off-label application of the PEG sealant.
View Article and Find Full Text PDFArticle Synopsis
- The Kidney Transplantation program at Policlinico University Hospital began in 1969, led by Professor Edmondo Malan, and has since completed a total of 2989 transplants by November 2011, with a majority from deceased donors.
- Advances in immunosuppressive drugs like cyclosporine and tacrolimus have notably improved both patient and graft survival rates, showing comparable outcomes for living and deceased donor recipients over several years.
- The program has adapted to use kidneys from older donors, with transplant success rates from donors aged 60 and above demonstrating survival rates similar to those of younger donors after five and ten years post-transplant.
The value of the resistive index (RI) obtained by echo color doppler evaluation of the transplanted kidney is still not well established. Many authors consider the RI to be nonspecific sign of rejection, acute tubular necrosis, or urinary tract obstruction, but its specificity remains low. In this paper, we report our experience with RI determinations in 34 consecutive kidney transplants at different times namely: perioperatively, at 24 hours, at 3 days, at 6 and at 9 days posttransplant.
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