Publications by authors named "A Pascale"

L. () is used in Italian folk medicine. This study was performed to determine genotoxic and antigenotoxic effects of leaf extract against mitomycin C (MMC) using an in vitro cytokinesis-block micronucleus assay (CBMN) in the Chinese Hamster Ovarian K1 (CHO-K1) cell line.

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Background: Early midlife individuals (ages 30-40) experience demographic shifts that may influence the remainder of adult life. Although new or persistent alcohol misuse is common during this period, early midlife is understudied in alcohol use literature. We examined the heritability of alcohol misuse; the associations between alcohol misuse and sociodemographic factors, physical health, and well-being; and whether these associations were robust in cotwin comparisons.

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Age-related macular degeneration (AMD) is the most common cause of irreversible loss of central vision in elderly subjects, affecting men and women equally. It is a degenerative pathology that causes progressive damage to the macula, the central and most vital part of the retina. There are two forms of AMD depending on how the macula is damaged, dry AMD and wet or neovascular AMD.

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Environmental noise, primarily attributed to the road transportation system, poses a significant challenge in Europe, impacting the quality of life for millions. Therefore, a thorough characterization of noise emissions from road transportation sources is needed to stem this problem. This investigation aims to fill a gap in the literature regarding single-vehicle noise emissions in the frequency domain.

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Article Synopsis
  • The gut microbiota-brain axis connects gut health to brain function, potentially influencing neurodegenerative diseases, particularly multiple sclerosis (MS).
  • MS is characterized by gastrointestinal issues and an altered gut microbiome compared to healthy individuals, which may worsen disease symptoms and progression.
  • The review discusses various dietary and microbiota-based interventions aimed at restoring gut health, which could help prevent or manage MS through symptom relief and slowing disease progression.
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